Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CHRNA3	HGNC:1957 (HGNC) 1136 (Entrez Gene) 118503 (OMIM) CHRNA3 (Alliance of Genome Resources)	Chr15 q25.1	Chr15:78593052-78621295 (-) GRCh38	alcohol dependence chronic obstructive pulmonary disease cocaine dependence lung adenocarcinoma lung cancer lung carcinoma lung non-small cell carcinoma lung small cell carcinoma nicotine dependence stomach cancer	P32297 (UniProt | EBI) NM_000743 (RefSeq)
mouse	Chrna3	MGI:87887 (MGI) 110834 (Entrez Gene) Gene Tree Chrna3 (Alliance of Genome Resources)	Chr9 29.84 cM	Chr9:54917401-54933846 (-) GRCm39		110834 (NCBI Gene Model) Q8R4G9 (UniProt | EBI) NM_145129 (RefSeq)
rat	Chrna3	RGD:2345 (Rat Genome Database) 25101 (Entrez Gene) Chrna3 (Alliance of Genome Resources)	Chr8 q24			P04757 (UniProt | EBI) NM_052805 (RefSeq)
zebrafish	chrna3	ZDB-GENE-070822-1 (Zebrafish Model Organism Database) 568467 (Entrez Gene) chrna3 (Alliance of Genome Resources)	Chr18			XP_001921314 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.