Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AFG3L2	HGNC:315 (HGNC) 10939 (Entrez Gene) 604581 (OMIM) AFG3L2 (Alliance of Genome Resources)	Chr18 p11.21	Chr18:12328944-12377227 (-) GRCh38	optic atrophy 12 spastic ataxia spastic ataxia 5 spinocerebellar ataxia type 28	Q9Y4W6 (UniProt | EBI) NM_006796 (RefSeq)
mouse	Afg3l2	MGI:1916847 (MGI) 69597 (Entrez Gene) Gene Tree Afg3l2 (Alliance of Genome Resources)	Chr18 39.96 cM	Chr18:67537834-67582242 (-) GRCm39	spinocerebellar ataxia type 28	ENSMUSG00000024527 (Ensembl Gene Model) ENSMUSP00000025408 (Ensembl) ENSMUST00000025408 (Ensembl)
rat	Afg3l2	RGD:1305259 (Rat Genome Database) 307350 (Entrez Gene) Afg3l2 (Alliance of Genome Resources)	Chr18 q12.1			NP_001128336 (RefSeq) NM_001134864 (RefSeq)
zebrafish	afg3l2	ZDB-GENE-070912-46 (Zebrafish Model Organism Database) 569168 (Entrez Gene) afg3l2 (Alliance of Genome Resources)	Chr2			NP_001104667 (RefSeq) NM_001111197 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.