Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HTR1A	HGNC:5286 (HGNC) 3350 (Entrez Gene) 109760 (OMIM) HTR1A (Alliance of Genome Resources)	Chr5 q12.3	Chr5:63957874-63962507 (-) GRCh38	alcohol dependence anxiety disorder depressive disorder panic disorder substance abuse withdrawal disorder	P08908 (UniProt | EBI) NM_000524 (RefSeq)
mouse	Htr1a	MGI:96273 (MGI) 15550 (Entrez Gene) Gene Tree Htr1a (Alliance of Genome Resources)	Chr13 56.92 cM	Chr13:105580147-105584630 (+) GRCm39	anxiety disorder	ENSMUSG00000021721 (Ensembl Gene Model) ENSMUSP00000022235 (Ensembl) ENSMUST00000022235 (Ensembl)
rat	Htr1a	RGD:2845 (Rat Genome Database) 24473 (Entrez Gene) Htr1a (Alliance of Genome Resources)	Chr2 q13			P19327 (UniProt | EBI) NM_012585 (RefSeq)
zebrafish	htr1aa	ZDB-GENE-071203-1 (Zebrafish Model Organism Database) 100001828 (Entrez Gene) htr1aa (Alliance of Genome Resources)	Chr8			NP_001116793 (RefSeq) NM_001123321 (RefSeq)
	htr1ab	ZDB-GENE-090409-2 (Zebrafish Model Organism Database) 797538 (Entrez Gene) htr1ab (Alliance of Genome Resources)	Chr21			NP_001139238 (RefSeq) NM_001145766 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.