Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL2RB	HGNC:6009 (HGNC) 3560 (Entrez Gene) 146710 (OMIM) IL2RB (Alliance of Genome Resources)	Chr22 q12.3	Chr22:37118666-37175118 (-) GRCh38	asthma immunodeficiency 63 myasthenia gravis visceral leishmaniasis	P14784 (UniProt | EBI) NM_001346222 (RefSeq)
mouse	Il2rb	MGI:96550 (MGI) 16185 (Entrez Gene) Gene Tree Il2rb (Alliance of Genome Resources)	Chr15 37.52 cM	Chr15:78363456-78379471 (-) GRCm39		ENSMUSG00000068227 (Ensembl Gene Model) ENSMUSP00000127006 (Ensembl) ENSMUST00000163494 (Ensembl)
rat	Il2rb	RGD:2896 (Rat Genome Database) 25746 (Entrez Gene) Il2rb (Alliance of Genome Resources)	Chr7			P26896 (UniProt | EBI) NM_013195 (RefSeq)
zebrafish	il2rb	ZDB-GENE-080108-2 (Zebrafish Model Organism Database) 793920 (Entrez Gene) il2rb (Alliance of Genome Resources)	Chr3			NP_001121739 (RefSeq) NM_001128267 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.