Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADORA2A	HGNC:263 (HGNC) 135 (Entrez Gene) 102776 (OMIM) ADORA2A (Alliance of Genome Resources)	Chr22 q11.23	Chr22:24417879-24442357 (+) GRCh38	asthma	P29274 (UniProt | EBI) NM_001278498 (RefSeq)
mouse	Adora2a	MGI:99402 (MGI) 11540 (Entrez Gene) Gene Tree Adora2a (Alliance of Genome Resources)	Chr10 38.52 cM	Chr10:75152711-75170618 (+) GRCm39	myopia primary pulmonary hypertension	ENSMUSG00000020178 (Ensembl Gene Model) ENSMUSP00000101060 (Ensembl) ENSMUST00000105420 (Ensembl)
rat	Adora2a	RGD:2049 (Rat Genome Database) 25369 (Entrez Gene) Adora2a (Alliance of Genome Resources)	Chr20 p12			P30543 (UniProt | EBI) NM_001357942 (RefSeq)
zebrafish	adora2aa	ZDB-GENE-080723-28 (Zebrafish Model Organism Database) 561701 (Entrez Gene) adora2aa (Alliance of Genome Resources)	Chr8			NP_001034904 (RefSeq) NM_001039815 (RefSeq)
	adora2ab	ZDB-GENE-081022-41 (Zebrafish Model Organism Database) 566118 (Entrez Gene) adora2ab (Alliance of Genome Resources)	Chr21			NP_001035125 (RefSeq) NM_001040036 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.