Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HTR1B	HGNC:5287 (HGNC) 3351 (Entrez Gene) 182131 (OMIM) HTR1B (Alliance of Genome Resources)	Chr6 q14.1	Chr6:77460924-77463491 (-) GRCh38	alcohol dependence alcohol use disorder antisocial personality disorder attention deficit hyperactivity disorder conduct disorder generalized anxiety disorder major depressive disorder nicotine dependence substance abuse	P28222 (UniProt | EBI) NM_000863 (RefSeq)
mouse	Htr1b	MGI:96274 (MGI) 15551 (Entrez Gene) Gene Tree Htr1b (Alliance of Genome Resources)	Chr9 44.61 cM	Chr9:81510344-81515881 (-) GRCm39		ENSMUSG00000049511 (Ensembl Gene Model) ENSMUSP00000139389 (Ensembl) ENSMUST00000183482 (Ensembl)
rat	Htr1b	RGD:2846 (Rat Genome Database) 25075 (Entrez Gene) Htr1b (Alliance of Genome Resources)	Chr8 q31			P28564 (UniProt | EBI) NM_022225 (RefSeq)
zebrafish	htr1b	ZDB-GENE-081022-141 (Zebrafish Model Organism Database) 561647 (Entrez Gene) htr1b (Alliance of Genome Resources)	Chr17			NP_001122181 (RefSeq) NM_001128709 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.