Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MUTYH	HGNC:7527 (HGNC) 4595 (Entrez Gene) 604933 (OMIM) MUTYH (Alliance of Genome Resources)	Chr1 p34.1	Chr1:45329163-45340893 (-) GRCh38	familial adenomatous polyposis familial adenomatous polyposis 2 stomach cancer stomach carcinoma	Q9UIF7 (UniProt | EBI) NM_001407089 (RefSeq)
mouse	Mutyh	MGI:1917853 (MGI) 70603 (Entrez Gene) Gene Tree Mutyh (Alliance of Genome Resources)	Chr4 53.34 cM	Chr4:116664920-116676637 (+) GRCm39		ENSMUSG00000028687 (Ensembl Gene Model) ENSMUSP00000099760 (Ensembl) ENSMUST00000102699 (Ensembl)
rat	Mutyh	RGD:620045 (Rat Genome Database) 170841 (Entrez Gene) Mutyh (Alliance of Genome Resources)	Chr5 q35			Q8R5G2 (UniProt | EBI) NM_133316 (RefSeq)
zebrafish	mutyh	ZDB-GENE-081104-193 (Zebrafish Model Organism Database) 558403 (Entrez Gene) mutyh (Alliance of Genome Resources)	Chr8			XP_068079228 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.