Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EFEMP1	HGNC:3218 (HGNC) 2202 (Entrez Gene) 601548 (OMIM) EFEMP1 (Alliance of Genome Resources)	Chr2 p16.1	Chr2:55865967-55924139 (-) GRCh38	cutis laxa Doyne honeycomb retinal dystrophy	Q12805 (UniProt | EBI) NM_018894 (RefSeq)
mouse	Efemp1	MGI:1339998 (MGI) 216616 (Entrez Gene) Gene Tree Efemp1 (Alliance of Genome Resources)	Chr11 16.32 cM	Chr11:28803204-28876743 (+) GRCm39	Doyne honeycomb retinal dystrophy	ENSMUSG00000020467 (Ensembl Gene Model) ENSMUSP00000020759 (Ensembl) ENSMUST00000020759 (Ensembl)
rat	Efemp1	RGD:1308528 (Rat Genome Database) 305604 (Entrez Gene) Efemp1 (Alliance of Genome Resources)	Chr14 q22			O35568 (UniProt | EBI) NM_001012039 (RefSeq)
zebrafish	efemp1	ZDB-GENE-130403-1 (Zebrafish Model Organism Database) 100332567 (Entrez Gene) efemp1 (Alliance of Genome Resources)	Chr13			XP_068069082 (RefSeq)
	si:ch73-173h19.3	ZDB-GENE-081104-245 (Zebrafish Model Organism Database) 563864 (Entrez Gene) si:ch73-173h19.3 (Alliance of Genome Resources)	Chr22			NP_001103991 (RefSeq) NM_001110521 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.