Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NECTIN1	HGNC:9706 (HGNC) 5818 (Entrez Gene) 600644 (OMIM) NECTIN1 (Alliance of Genome Resources)	Chr11 q23.3	Chr11:119623408-119729200 (-) GRCh38	cleft lip cleft lip-palate-ectodermal dysplasia syndrome cleft palate ectodermal dysplasia	Q15223 (UniProt | EBI) NM_002855 (RefSeq)
mouse	Nectin1	MGI:1926483 (MGI) 58235 (Entrez Gene) Gene Tree Nectin1 (Alliance of Genome Resources)	Chr9 24.42 cM	Chr9:43655251-43718758 (+) GRCm39		58235 (NCBI Gene Model) Q9JKF6 (UniProt | EBI) NM_021424 (RefSeq)
rat	Nectin1	RGD:620791 (Rat Genome Database) 192183 (Entrez Gene) Nectin1 (Alliance of Genome Resources)	Chr8 q22			NP_001093946 (RefSeq) NM_001100476 (RefSeq)
zebrafish	nectin1a	ZDB-GENE-090224-1 (Zebrafish Model Organism Database) 100136836 (Entrez Gene) nectin1a (Alliance of Genome Resources)	Chr21			NP_001161042 (RefSeq) NM_001167570 (RefSeq)
	nectin1b	ZDB-GENE-090224-2 (Zebrafish Model Organism Database) 557665 (Entrez Gene) nectin1b (Alliance of Genome Resources)	Chr18			NP_001161041 (RefSeq) NM_001167569 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.