Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TET2	HGNC:25941 (HGNC) 54790 (Entrez Gene) 612839 (OMIM) TET2 (Alliance of Genome Resources)	Chr4 q24	Chr4:105145875-105279816 (+) GRCh38	acute myeloid leukemia chronic myelomonocytic leukemia esophagus squamous cell carcinoma hepatocellular carcinoma lung non-small cell carcinoma myelodysplastic syndrome myeloproliferative neoplasm nasopharynx carcinoma primary immunodeficiency disease stomach cancer	Q6N021 (UniProt | EBI) NM_017628 (RefSeq)
mouse	Tet2	MGI:2443298 (MGI) 214133 (Entrez Gene) Gene Tree Tet2 (Alliance of Genome Resources)	Chr3 61.84 cM	Chr3:133169438-133250882 (-) GRCm39		214133 (NCBI Gene Model) Q4JK59 (UniProt | EBI) NM_001346736 (RefSeq)
rat	Tet2	RGD:1311625 (Rat Genome Database) 310859 (Entrez Gene) Tet2 (Alliance of Genome Resources)	Chr2 q43			NP_001414486 (RefSeq) NM_001427557 (RefSeq)
zebrafish	tet2	ZDB-GENE-090312-98 (Zebrafish Model Organism Database) 101887161 (Entrez Gene) tet2 (Alliance of Genome Resources)	Chr1			XP_005159960 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.