Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SAMHD1	HGNC:15925 (HGNC) 25939 (Entrez Gene) 606754 (OMIM) SAMHD1 (Alliance of Genome Resources)	Chr20 q11.23	Chr20:36889773-36951893 (-) GRCh38	acute myeloid leukemia Aicardi-Goutieres syndrome Chilblain lupus hepatitis B hepatitis C	Q9Y3Z3 (UniProt | EBI) NM_001363733 (RefSeq)
mouse	Samhd1	MGI:1927468 (MGI) 56045 (Entrez Gene) Gene Tree Samhd1 (Alliance of Genome Resources)	Chr2 78.0 cM	Chr2:156939454-156977016 (-) GRCm39		56045 (NCBI Gene Model) Q60710 (UniProt | EBI) NM_001139520 (RefSeq)
rat	Samhd1	RGD:1308369 (Rat Genome Database) 311580 (Entrez Gene) Samhd1 (Alliance of Genome Resources)	Chr3 q42			NP_001178672 (RefSeq) NM_001191743 (RefSeq)
zebrafish	samhd1	ZDB-GENE-090313-386 (Zebrafish Model Organism Database) 553453 (Entrez Gene) samhd1 (Alliance of Genome Resources)	Chr23			Q502K2 (UniProt | EBI) NM_001159933 (RefSeq)
	si:ch211-233g6.2	ZDB-GENE-121214-114 (Zebrafish Model Organism Database) 100333959 (Entrez Gene) si:ch211-233g6.2 (Alliance of Genome Resources)	Chr1			XP_068076982 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.