Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MEGF8	HGNC:3233 (HGNC) 1954 (Entrez Gene) 604267 (OMIM) MEGF8 (Alliance of Genome Resources)	Chr19 q13.2	Chr19:42325609-42378769 (+) GRCh38	Carpenter syndrome	Q7Z7M0 (UniProt | EBI) NM_001271938 (RefSeq)
mouse	Megf8	MGI:2446294 (MGI) 269878 (Entrez Gene) Gene Tree Megf8 (Alliance of Genome Resources)	Chr7 13.75 cM	Chr7:25016589-25065342 (+) GRCm39	Carpenter syndrome visceral heterotaxy	269878 (NCBI Gene Model) P60882 (UniProt | EBI) NM_001160400 (RefSeq)
rat	Megf8	RGD:621190 (Rat Genome Database) 114029 (Entrez Gene) Megf8 (Alliance of Genome Resources)	Chr1 q21			Q9QYP0 (UniProt | EBI) NM_053628 (RefSeq)
zebrafish	megf8	ZDB-GENE-090730-1 (Zebrafish Model Organism Database) 791154 (Entrez Gene) megf8 (Alliance of Genome Resources)	Chr16			XP_005158088 (RefSeq) NM_001080636 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.