Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TCF4	HGNC:11634 (HGNC) 6925 (Entrez Gene) 602272 (OMIM) TCF4 (Alliance of Genome Resources)	Chr18 q21.2	Chr18:55222185-55664787 (-) GRCh38	Fuchs' endothelial dystrophy Lynch syndrome Pitt-Hopkins syndrome	P15884 (UniProt | EBI) NM_001348220 (RefSeq)
mouse	Tcf4	MGI:98506 (MGI) 21413 (Entrez Gene) Gene Tree Tcf4 (Alliance of Genome Resources)	Chr18 43.23 cM	Chr18:69476500-69821038 (+) GRCm39	Pitt-Hopkins syndrome schizophrenia	21413 (NCBI Gene Model) Q60722 (UniProt | EBI) NM_013685 (RefSeq)
rat	Tcf4	RGD:69271 (Rat Genome Database) 84382 (Entrez Gene) Tcf4 (Alliance of Genome Resources)	Chr18 q12.1			Q62655 (UniProt | EBI) NM_053369 (RefSeq)
zebrafish	tcf4	ZDB-GENE-090814-1 (Zebrafish Model Organism Database) 100526651 (Entrez Gene) tcf4 (Alliance of Genome Resources)	Chr21			XP_021324617 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.