Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDE1C	HGNC:8776 (HGNC) 5137 (Entrez Gene) 602987 (OMIM) PDE1C (Alliance of Genome Resources)	Chr7 p14.3	Chr7:31616777-32428224 (-) GRCh38	autosomal dominant nonsyndromic deafness 74	Q14123 (UniProt | EBI) NM_005020 (RefSeq)
mouse	Pde1c	MGI:108413 (MGI) 18575 (Entrez Gene) Gene Tree Pde1c (Alliance of Genome Resources)	Chr6 27.65 cM	Chr6:56046789-56629472 (-) GRCm39		ENSMUSG00000004347 (Ensembl Gene Model) ENSMUSP00000158960 (Ensembl) ENSMUST00000239143 (Ensembl)
rat	Pde1c	RGD:68332 (Rat Genome Database) 81742 (Entrez Gene) Pde1c (Alliance of Genome Resources)	Chr4 q24			Q63421 (UniProt | EBI) NM_031078 (RefSeq)
zebrafish	pde1ca	ZDB-GENE-111215-4 (Zebrafish Model Organism Database) 101883995 (Entrez Gene) pde1ca (Alliance of Genome Resources)	Chr24			XP_021326050 (RefSeq)
	pde1cb	ZDB-GENE-090902-2 (Zebrafish Model Organism Database) 100536162 (Entrez Gene) pde1cb (Alliance of Genome Resources)	Chr2			XP_009297150 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.