Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DSG2	HGNC:3049 (HGNC) 1829 (Entrez Gene) 125671 (OMIM) DSG2 (Alliance of Genome Resources)	Chr18 q12.1	Chr18:31497624-31551351 (+) GRCh38	arrhythmogenic right ventricular cardiomyopathy arrhythmogenic right ventricular dysplasia 10 dilated cardiomyopathy dilated cardiomyopathy 1BB	Q14126 (UniProt | EBI) NM_001943 (RefSeq)
mouse	Dsg2	MGI:1196466 (MGI) 13511 (Entrez Gene) Gene Tree Dsg2 (Alliance of Genome Resources)	Chr18 11.42 cM	Chr18:20691247-20737583 (+) GRCm39	arrhythmogenic right ventricular cardiomyopathy arrhythmogenic right ventricular dysplasia 10 intrinsic cardiomyopathy	13511 (NCBI Gene Model) O55111 (UniProt | EBI) NM_007883 (RefSeq)
rat	Dsg2	RGD:1311143 (Rat Genome Database) 307562 (Entrez Gene) Dsg2 (Alliance of Genome Resources)	Chr18 p12			NP_001414207 (RefSeq) NM_001427278 (RefSeq)
zebrafish	si:ch73-74h11.1	ZDB-GENE-091204-215 (Zebrafish Model Organism Database) 100534918 (Entrez Gene) si:ch73-74h11.1 (Alliance of Genome Resources)	Chr20			XP_017208205 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.