Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MAPKAPK2	HGNC:6887 (HGNC) 9261 (Entrez Gene) 602006 (OMIM) MAPKAPK2 (Alliance of Genome Resources)	Chr1 q32.1	Chr1:206684905-206734281 (+) GRCh38		P49137 (UniProt | EBI) NM_004759 (RefSeq)
mouse	Mapkapk2	MGI:109298 (MGI) 17164 (Entrez Gene) Gene Tree Mapkapk2 (Alliance of Genome Resources)	Chr1 56.89 cM	Chr1:130981437-131025563 (-) GRCm39		ENSMUSG00000016528 (Ensembl Gene Model) ENSMUSP00000016672 (Ensembl) ENSMUST00000016672 (Ensembl)
rat	Mapkapk2	RGD:631362 (Rat Genome Database) 289014 (Entrez Gene) Mapkapk2 (Alliance of Genome Resources)	Chr13 q13			NP_835203 (RefSeq) NM_178102 (RefSeq)
zebrafish	mapkapk2a	ZDB-GENE-030131-5532 (Zebrafish Model Organism Database) 327321 (Entrez Gene) mapkapk2a (Alliance of Genome Resources)	Chr11			NP_958460 (RefSeq) NM_201303 (RefSeq)
	mapkapk2b	ZDB-GENE-071018-1 (Zebrafish Model Organism Database) 557648 (Entrez Gene) mapkapk2b (Alliance of Genome Resources)	Chr8			NP_001095273 (RefSeq) NM_001101803 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.