Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GDF2	HGNC:4217 (HGNC) 2658 (Entrez Gene) 605120 (OMIM) GDF2 (Alliance of Genome Resources)	Chr10 q11.22	Chr10:47322454-47327588 (+) GRCh38	hereditary hemorrhagic telangiectasia	Q9UK05 (UniProt | EBI) NM_016204 (RefSeq)
mouse	Gdf2	MGI:1321394 (MGI) 12165 (Entrez Gene) Gene Tree Gdf2 (Alliance of Genome Resources)	Chr14 20.8 cM	Chr14:33662996-33669155 (+) GRCm39		12165 (NCBI Gene Model) Q9WV56 (UniProt | EBI) NM_019506 (RefSeq)
rat	Gdf2	RGD:1586196 (Rat Genome Database) 290921 (Entrez Gene) Gdf2 (Alliance of Genome Resources)	Chr16			NP_001099566 (RefSeq) NM_001106096 (RefSeq)
zebrafish	gdf2	ZDB-GENE-100107-1 (Zebrafish Model Organism Database) 563287 (Entrez Gene) gdf2 (Alliance of Genome Resources)	Chr12			F1QWZ4 (UniProt | EBI) NM_001171586 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.