Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL4	HGNC:6014 (HGNC) 3565 (Entrez Gene) 147780 (OMIM) IL4 (Alliance of Genome Resources)	Chr5 q31.1	Chr5:132673986-132682678 (+) GRCh38	Alzheimer's disease aspirin-induced respiratory disease asthma atopic dermatitis autoimmune hepatitis autoimmune thrombocytopenic purpura Behcet's disease biliary tract benign neoplasm hepatitis B hepatitis C multiple sclerosis pancreatic cancer pancreatic ductal carcinoma temporal arteritis	P05112 (UniProt | EBI) NM_000589 (RefSeq)
mouse	Il4	MGI:96556 (MGI) 16189 (Entrez Gene) Gene Tree Il4 (Alliance of Genome Resources)	Chr11 31.97 cM	Chr11:53503287-53509492 (-) GRCm39	atopic dermatitis Sjogren's syndrome type 1 diabetes mellitus	16189 (NCBI Gene Model) P07750 (UniProt | EBI) NR_027491 (RefSeq)
rat	Il4	RGD:2898 (Rat Genome Database) 287287 (Entrez Gene) Il4 (Alliance of Genome Resources)	Chr10 q22			P20096 (UniProt | EBI) NM_201270 (RefSeq)
zebrafish	il4	ZDB-GENE-100204-1 (Zebrafish Model Organism Database) 100188894 (Entrez Gene) il4 (Alliance of Genome Resources)	Chr14			NP_001164211 (RefSeq) NM_001170740 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.