Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	USP45	HGNC:20080 (HGNC) 85015 (Entrez Gene) 618439 (OMIM) USP45 (Alliance of Genome Resources)	Chr6 q16.2	Chr6:99432325-99521728 (-) GRCh38	Leber congenital amaurosis 19	Q70EL2 (UniProt | EBI) NM_001346029 (RefSeq)
mouse	Usp45	MGI:101850 (MGI) 77593 (Entrez Gene) Gene Tree Usp45 (Alliance of Genome Resources)	Chr4 8.93 cM	Chr4:21767161-21837872 (+) GRCm39	Leber congenital amaurosis 19	77593 (NCBI Gene Model) Q8K387 (UniProt | EBI) NM_152825 (RefSeq)
rat	Usp45	RGD:1310976 (Rat Genome Database) 313098 (Entrez Gene) Usp45 (Alliance of Genome Resources)	Chr5 q21			NP_001382490 (RefSeq) NM_001395561 (RefSeq)
zebrafish	usp45	ZDB-GENE-100211-2 (Zebrafish Model Organism Database) 564004 (Entrez Gene) usp45 (Alliance of Genome Resources)	Chr16			E9QG68 (UniProt | EBI) NM_001423966 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.