Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SPG11	HGNC:11226 (HGNC) 80208 (Entrez Gene) 610844 (OMIM) SPG11 (Alliance of Genome Resources)	Chr15 q21.1		amyotrophic lateral sclerosis type 5 Charcot-Marie-Tooth disease axonal type 2X hereditary spastic paraplegia 11	Q96JI7 (UniProt | EBI) NM_001411132 (RefSeq)
mouse	Spg11	MGI:2444989 (MGI) 214585 (Entrez Gene) Gene Tree Spg11 (Alliance of Genome Resources)	Chr2 60.5 cM	Chr2:121884001-121948867 (-) GRCm39	hereditary spastic paraplegia 11	ENSMUSG00000033396 (Ensembl Gene Model) ENSMUSP00000037543 (Ensembl) ENSMUST00000036450 (Ensembl)
rat	Spg11	RGD:1562529 (Rat Genome Database) 311372 (Entrez Gene) Spg11 (Alliance of Genome Resources)	Chr3 q35			NP_001402853 (RefSeq) NM_001191571 (RefSeq)
zebrafish	spg11	ZDB-GENE-101017-1 (Zebrafish Model Organism Database) 793551 (Entrez Gene) spg11 (Alliance of Genome Resources)	Chr25			NP_001181923 (RefSeq) NM_001194994 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.