Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ITGB2	HGNC:6155 (HGNC) 3689 (Entrez Gene) 600065 (OMIM) ITGB2 (Alliance of Genome Resources)	Chr21 q22.3	Chr21:44885953-44931989 (-) GRCh38	coronary restenosis leukocyte adhesion deficiency leukocyte adhesion deficiency 1	P05107 (UniProt | EBI) NM_000211 (RefSeq)
mouse	Itgb2	MGI:96611 (MGI) 16414 (Entrez Gene) Gene Tree Itgb2 (Alliance of Genome Resources)	Chr10 39.72 cM	Chr10:77366164-77401542 (+) GRCm39	leukocyte adhesion deficiency 1 psoriasis	16414 (NCBI Gene Model) P11835 (UniProt | EBI) NM_008404 (RefSeq)
rat	Itgb2	RGD:1305581 (Rat Genome Database) 309684 (Entrez Gene) Itgb2 (Alliance of Genome Resources)	Chr20 p12			NP_001032869 (RefSeq) NM_001037780 (RefSeq)
zebrafish	itgb2	ZDB-GENE-110411-4 (Zebrafish Model Organism Database) 557797 (Entrez Gene) itgb2 (Alliance of Genome Resources)	Chr9			XP_686012 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.