Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IL6ST	HGNC:6021 (HGNC) 3572 (Entrez Gene) 600694 (OMIM) IL6ST (Alliance of Genome Resources)	Chr5 q11.2	Chr5:55935095-55995022 (-) GRCh38	arteriosclerosis hyperandrogenism hyper IgE recurrent infection syndrome 4 primary immunodeficiency disease	P40189 (UniProt | EBI) NM_001364275 (RefSeq)
mouse	Il6st	MGI:96560 (MGI) 16195 (Entrez Gene) Gene Tree Il6st (Alliance of Genome Resources)	Chr13 63.73 cM	Chr13:112600604-112643394 (+) GRCm39	rheumatoid arthritis stomach cancer	16195 (NCBI Gene Model) Q00560 (UniProt | EBI) NM_010560 (RefSeq)
rat	Il6st	RGD:2903 (Rat Genome Database) 25205 (Entrez Gene) Il6st (Alliance of Genome Resources)	Chr2 q14			P40190 (UniProt | EBI) NM_001008725 (RefSeq)
zebrafish	il6st	ZDB-GENE-080104-6 (Zebrafish Model Organism Database) 100006778 (Entrez Gene) il6st (Alliance of Genome Resources)	Chr10			NP_001106976 (RefSeq) NM_001113504 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.