Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MLC1	HGNC:17082 (HGNC) 23209 (Entrez Gene) 605908 (OMIM) MLC1 (Alliance of Genome Resources)	Chr22 q13.33	Chr22:50059391-50085875 (-) GRCh38	megalencephalic leukoencephalopathy with subcortical cysts 1	Q15049 (UniProt | EBI) NM_001376479 (RefSeq)
mouse	Mlc1	MGI:2157910 (MGI) 170790 (Entrez Gene) Gene Tree Mlc1 (Alliance of Genome Resources)	Chr15 44.46 cM	Chr15:88840087-88863192 (-) GRCm39	megalencephalic leukoencephalopathy with subcortical cysts 1	170790 (NCBI Gene Model) Q8VHK5 (UniProt | EBI) NM_001364855 (RefSeq)
rat	Mlc1	RGD:1308552 (Rat Genome Database) 315215 (Entrez Gene) Mlc1 (Alliance of Genome Resources)	Chr7 q34			NP_001101575 (RefSeq) NM_001108105 (RefSeq)
zebrafish	mlc1	ZDB-GENE-050419-145 (Zebrafish Model Organism Database) 559990 (Entrez Gene) mlc1 (Alliance of Genome Resources)	Chr18			NP_001098409 (RefSeq) NM_001104939 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.