Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CHRNB4	HGNC:1964 (HGNC) 1143 (Entrez Gene) 118509 (OMIM) CHRNB4 (Alliance of Genome Resources)	Chr15 q25.1	Chr15:78624111-78727754 (-) GRCh38	cocaine abuse lung adenocarcinoma lung cancer lung non-small cell carcinoma lung squamous cell carcinoma nicotine dependence oral cavity cancer	P30926 (UniProt | EBI) NM_001256567 (RefSeq)
mouse	Chrnb4	MGI:87892 (MGI) 108015 (Entrez Gene) Gene Tree Chrnb4 (Alliance of Genome Resources)	Chr9 29.84 cM	Chr9:54935438-54956063 (-) GRCm39		ENSMUSG00000035200 (Ensembl Gene Model) ENSMUSP00000034854 (Ensembl) ENSMUST00000034854 (Ensembl)
rat	Chrnb4	RGD:2351 (Rat Genome Database) 25103 (Entrez Gene) Chrnb4 (Alliance of Genome Resources)	Chr8 q24			P12392 (UniProt | EBI) NM_052806 (RefSeq)
zebrafish	chrnb4	ZDB-GENE-120809-1 (Zebrafish Model Organism Database) 568566 (Entrez Gene) chrnb4 (Alliance of Genome Resources)	Chr18			XP_696993 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.