Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CLDN22	HGNC:2044 (HGNC) 53842 (Entrez Gene) 620566 (OMIM) CLDN22 (Alliance of Genome Resources)	Chr4 q35.1	Chr4:183318100-183320276 (-) GRCh38		Q8N7P3 (UniProt | EBI) NM_001111319 (RefSeq)
mouse	Cldn22	MGI:1922927 (MGI) 75677 (Entrez Gene) Gene Tree Cldn22 (Alliance of Genome Resources)	Chr8 26.91 cM	Chr8:48277517-48278511 (+) GRCm39		ENSMUSG00000038064 (Ensembl Gene Model) ENSMUSP00000041676 (Ensembl) ENSMUST00000038693 (Ensembl)
rat	Cldn22	RGD:1305271 (Rat Genome Database) 306454 (Entrez Gene) Cldn22 (Alliance of Genome Resources)	Chr16 q11			NP_001103613 (RefSeq) NM_001110143 (RefSeq)
zebrafish	cldn26	ZDB-GENE-060526-352 (Zebrafish Model Organism Database) 793143 (Entrez Gene) cldn26 (Alliance of Genome Resources)	Chr5			NP_001116178 (RefSeq) NM_001122706 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.