Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FIG4	HGNC:16873 (HGNC) 9896 (Entrez Gene) 609390 (OMIM) FIG4 (Alliance of Genome Resources)	Chr6 q21	Chr6:109690609-109878098 (+) GRCh38	amyotrophic lateral sclerosis type 11 bilateral parasagittal parieto-occipital polymicrogyria Charcot-Marie-Tooth disease type 4J Yunis-Varon syndrome	Q92562 (UniProt | EBI) NM_014845 (RefSeq)
mouse	Fig4	MGI:2143585 (MGI) 103199 (Entrez Gene) Gene Tree Fig4 (Alliance of Genome Resources)	Chr10 22.08 cM	Chr10:41064168-41179237 (-) GRCm39	Charcot-Marie-Tooth disease type 4J Yunis-Varon syndrome	103199 (NCBI Gene Model) Q91WF7 (UniProt | EBI) NM_133999 (RefSeq)
rat	Fig4	RGD:1311375 (Rat Genome Database) 309855 (Entrez Gene) Fig4 (Alliance of Genome Resources)	Chr20 q12			NP_001040561 (RefSeq) NM_001047096 (RefSeq)
zebrafish	fig4a	ZDB-GENE-130213-1 (Zebrafish Model Organism Database) 100334605 (Entrez Gene) fig4a (Alliance of Genome Resources)	Chr20			XP_021324400 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.