Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SHOX2	HGNC:10854 (HGNC) 6474 (Entrez Gene) 602504 (OMIM) SHOX2 (Alliance of Genome Resources)	Chr3 q25.32	Chr3:158095905-158106420 (-) GRCh38	lung cancer	O60902 (UniProt | EBI) NM_006884 (RefSeq)
mouse	Shox2	MGI:1201673 (MGI) 20429 (Entrez Gene) Gene Tree Shox2 (Alliance of Genome Resources)	Chr3 30.76 cM	Chr3:66879060-66889104 (-) GRCm39	Leri-Weill dyschondrosteosis	ENSMUSG00000027833 (Ensembl Gene Model) ENSMUSP00000029422 (Ensembl) ENSMUST00000029422 (Ensembl)
rat	Shox2	RGD:3674 (Rat Genome Database) 25546 (Entrez Gene) Shox2 (Alliance of Genome Resources)	Chr2 q31			O35750 (UniProt | EBI) NM_013028 (RefSeq)
zebrafish	shox2	ZDB-GENE-040426-1457 (Zebrafish Model Organism Database) 394171 (Entrez Gene) shox2 (Alliance of Genome Resources)	Chr15			NP_957490 (RefSeq) NM_201196 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.