Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SIK3	HGNC:29165 (HGNC) 23387 (Entrez Gene) 614776 (OMIM) SIK3 (Alliance of Genome Resources)	Chr11 q23.3	Chr11:116843402-117098437 (-) GRCh38		Q9Y2K2 (UniProt | EBI) NM_001366686 (RefSeq)
mouse	Sik3	MGI:2446296 (MGI) 70661 (Entrez Gene) Gene Tree Sik3 (Alliance of Genome Resources)	Chr9 25.36 cM	Chr9:45924118-46135492 (+) GRCm39		ENSMUSG00000034135 (Ensembl Gene Model) ENSMUSP00000121032 (Ensembl) ENSMUST00000126865 (Ensembl)
rat	Sik3	RGD:1593938 (Rat Genome Database) 684112 (Entrez Gene) Sik3 (Alliance of Genome Resources)	Chr8			NP_001258145 (RefSeq) NM_001271216 (RefSeq)
zebrafish	sik3	ZDB-GENE-140106-203 (Zebrafish Model Organism Database) 393513 (Entrez Gene) sik3 (Alliance of Genome Resources)	Chr15			Q6NSM8 (UniProt | EBI) NM_200541 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.