Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CHRNA1	HGNC:1955 (HGNC) 1134 (Entrez Gene) 100690 (OMIM) CHRNA1 (Alliance of Genome Resources)	Chr2 q31.1	Chr2:174747592-174787935 (-) GRCh38	congenital myasthenic syndrome 1A congenital myasthenic syndrome 1B	P02708 (UniProt | EBI) NM_000079 (RefSeq)
mouse	Chrna1	MGI:87885 (MGI) 11435 (Entrez Gene) Gene Tree Chrna1 (Alliance of Genome Resources)	Chr2 43.76 cM	Chr2:73393625-73410682 (-) GRCm39		11435 (NCBI Gene Model) P04756 (UniProt | EBI) NM_007389 (RefSeq)
rat	Chrna1	RGD:69277 (Rat Genome Database) 79557 (Entrez Gene) Chrna1 (Alliance of Genome Resources)	Chr3 q23			P25108 (UniProt | EBI) NM_024485 (RefSeq)
zebrafish	chrna1	ZDB-GENE-980526-137 (Zebrafish Model Organism Database) 30725 (Entrez Gene) chrna1 (Alliance of Genome Resources)	Chr6			Q98880 (UniProt | EBI) NM_131445 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.