Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HOXB8	HGNC:5119 (HGNC) 3218 (Entrez Gene) 142963 (OMIM) HOXB8 (Alliance of Genome Resources)	Chr17 q21.32	Chr17:48611377-48615292 (-) GRCh38		P17481 (UniProt | EBI) NM_024016 (RefSeq)
mouse	Hoxb8	MGI:96189 (MGI) 15416 (Entrez Gene) Gene Tree Hoxb8 (Alliance of Genome Resources)	Chr11 59.82 cM	Chr11:96172731-96176141 (+) GRCm39	trichotillomania	ENSMUSG00000056648 (Ensembl Gene Model) ENSMUSP00000052496 (Ensembl) ENSMUST00000052650 (Ensembl)
rat	Hoxb8	RGD:1586211 (Rat Genome Database) 24457 (Entrez Gene) Hoxb8 (Alliance of Genome Resources)	Chr10 q26			P18863 (UniProt | EBI) NM_001191649 (RefSeq)
zebrafish	hoxb8a	ZDB-GENE-990415-108 (Zebrafish Model Organism Database) 30343 (Entrez Gene) hoxb8a (Alliance of Genome Resources)	Chr3			Q8AWZ0 (UniProt | EBI) NM_131120 (RefSeq)
	hoxb8b	ZDB-GENE-980526-291 (Zebrafish Model Organism Database) 30420 (Entrez Gene) hoxb8b (Alliance of Genome Resources)	Chr12			Q8JH55 (UniProt | EBI) NM_131181 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.