Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MSX1	HGNC:7391 (HGNC) 4487 (Entrez Gene) 142983 (OMIM) MSX1 (Alliance of Genome Resources)	Chr4 p16.2	Chr4:4859665-4863936 (+) GRCh38	anodontia cleft lip cleft palate orofacial cleft 5 tooth agenesis tooth and nail syndrome	P28360 (UniProt | EBI) NM_002448 (RefSeq)
mouse	Msx1	MGI:97168 (MGI) 17701 (Entrez Gene) Gene Tree Msx1 (Alliance of Genome Resources)	Chr5 20.21 cM	Chr5:37977835-37981929 (-) GRCm39	orofacial cleft tooth agenesis	17701 (NCBI Gene Model) P13297 (UniProt | EBI) NM_010835 (RefSeq)
rat	Msx1	RGD:620929 (Rat Genome Database) 81710 (Entrez Gene) Msx1 (Alliance of Genome Resources)	Chr14 q21			NP_112321 (RefSeq) NM_031059 (RefSeq)
zebrafish	msx1a	ZDB-GENE-980526-312 (Zebrafish Model Organism Database) 30527 (Entrez Gene) msx1a (Alliance of Genome Resources)	Chr14			NP_571348 (RefSeq) NM_001033589 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.