Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CTNNB1	HGNC:2514 (HGNC) 1499 (Entrez Gene) 116806 (OMIM) CTNNB1 (Alliance of Genome Resources)	Chr3 p22.1	Chr3:41194741-41260096 (+) GRCh38	autosomal dominant intellectual developmental disorder 19 colorectal cancer exudative vitreoretinopathy 7 fibrolamellar carcinoma hepatocellular carcinoma medulloblastoma nephroblastoma ovarian cancer pilomatrixoma	P35222 (UniProt | EBI) NM_001098209 (RefSeq)
mouse	Ctnnb1	MGI:88276 (MGI) 12387 (Entrez Gene) Gene Tree Ctnnb1 (Alliance of Genome Resources)	Chr9 72.19 cM	Chr9:120762466-120789573 (+) GRCm39	autism spectrum disorder exudative vitreoretinopathy granulosa cell tumor ovarian cancer prostate cancer urinary bladder cancer	12387 (NCBI Gene Model) Q02248 (UniProt | EBI) NM_001431672 (RefSeq)
rat	Ctnnb1	RGD:70487 (Rat Genome Database) 84353 (Entrez Gene) Ctnnb1 (Alliance of Genome Resources)	Chr8 q32			Q9WU82 (UniProt | EBI) NM_001431667 (RefSeq)
zebrafish	ctnnb1	ZDB-GENE-980526-362 (Zebrafish Model Organism Database) 30265 (Entrez Gene) ctnnb1 (Alliance of Genome Resources)	Chr16			F1QGH7 (UniProt | EBI) NM_131059 (RefSeq)
	ctnnb2	ZDB-GENE-040426-2575 (Zebrafish Model Organism Database) 324004 (Entrez Gene) ctnnb2 (Alliance of Genome Resources)	Chr19			NP_001001889 (RefSeq) NM_001001889 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.