Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SOX3	HGNC:11199 (HGNC) 6658 (Entrez Gene) 313430 (OMIM) SOX3 (Alliance of Genome Resources)	ChrX q27.1	ChrX:140502985-140505069 (-) GRCh38	X-linked panhypopituitarism	P41225 (UniProt | EBI) NM_005634 (RefSeq)
mouse	Sox3	MGI:98365 (MGI) 20675 (Entrez Gene) Gene Tree Sox3 (Alliance of Genome Resources)	ChrX 33.66 cM	ChrX:59934972-59937036 (-) GRCm39	hydrocephalus	ENSMUSG00000045179 (Ensembl Gene Model) ENSMUSP00000115237 (Ensembl) ENSMUST00000135107 (Ensembl)
zebrafish	sox3	ZDB-GENE-980526-333 (Zebrafish Model Organism Database) 30529 (Entrez Gene) sox3 (Alliance of Genome Resources)	Chr14			Q6EJB7 (UniProt | EBI) NM_001001811 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.