Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SMO	HGNC:11119 (HGNC) 6608 (Entrez Gene) 601500 (OMIM) SMO (Alliance of Genome Resources)	Chr7 q32.1	Chr7:129188633-129213545 (+) GRCh38	basal cell carcinoma hepatocellular carcinoma malignant pleural mesothelioma pancreatic cancer pancreatic ductal carcinoma	Q99835 (UniProt | EBI) NM_005631 (RefSeq)
mouse	Smo	MGI:108075 (MGI) 319757 (Entrez Gene) Gene Tree Smo (Alliance of Genome Resources)	Chr6 12.36 cM	Chr6:29735502-29761364 (+) GRCm39	medulloblastoma pulmonary emphysema	ENSMUSG00000001761 (Ensembl Gene Model) ENSMUSP00000001812 (Ensembl) ENSMUST00000001812 (Ensembl)
rat	Smo	RGD:3726 (Rat Genome Database) 25273 (Entrez Gene) Smo (Alliance of Genome Resources)	Chr4 q22			P97698 (UniProt | EBI) NM_012807 (RefSeq)
zebrafish	smo	ZDB-GENE-980526-89 (Zebrafish Model Organism Database) 30225 (Entrez Gene) smo (Alliance of Genome Resources)	Chr4			Q5RH73 (UniProt | EBI) NM_131027 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.