Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SOD1	HGNC:11179 (HGNC) 6647 (Entrez Gene) 147450 (OMIM) SOD1 (Alliance of Genome Resources)	Chr21 q22.11	Chr21:31659666-31668931 (+) GRCh38	amyotrophic lateral sclerosis amyotrophic lateral sclerosis type 1 cataract diabetic retinopathy Down syndrome hyperglycemia hypertension motor neuron disease myocardial infarction newborn respiratory distress syndrome Parkinson's disease prion disease retinitis pigmentosa retinopathy of prematurity sciatic neuropathy transient cerebral ischemia type 1 diabetes mellitus type 2 diabetes mellitus	P00441 (UniProt | EBI) NM_000454 (RefSeq)
mouse	Sod1	MGI:98351 (MGI) 20655 (Entrez Gene) Gene Tree Sod1 (Alliance of Genome Resources)	Chr16 51.56 cM	Chr16:90017650-90023221 (+) GRCm39	amyotrophic lateral sclerosis type 1 dry eye syndrome low tension glaucoma	20655 (NCBI Gene Model) P08228 (UniProt | EBI) NM_011434 (RefSeq)
rat	Sod1	RGD:3731 (Rat Genome Database) 24786 (Entrez Gene) Sod1 (Alliance of Genome Resources)	Chr11 q11			P07632 (UniProt | EBI) NM_017050 (RefSeq)
zebrafish	sod1	ZDB-GENE-990415-258 (Zebrafish Model Organism Database) 30553 (Entrez Gene) sod1 (Alliance of Genome Resources)	Chr10			O73872 (UniProt | EBI) NM_131294 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.