Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ACAT2	HGNC:94 (HGNC) 39 (Entrez Gene) 100678 (OMIM) ACAT2 (Alliance of Genome Resources)	Chr6 q25.3	Chr6:159762045-159779112 (+) GRCh38	coronary artery disease	Q9BWD1 (UniProt | EBI) NM_001303253 (RefSeq)
mouse	Acat2	MGI:87871 (MGI) 110460 (Entrez Gene) Gene Tree Acat2 (Alliance of Genome Resources)	Chr17 8.73 cM	Chr17:13161929-13179612 (-) GRCm39		110460 (NCBI Gene Model) Q8CAY6 (UniProt | EBI) NM_009338 (RefSeq)
rat	Acat2	RGD:1359366 (Rat Genome Database) 308100 (Entrez Gene) Acat2 (Alliance of Genome Resources)	Chr1 q11			Q5XI22 (UniProt | EBI) NM_001006995 (RefSeq)
zebrafish	acat2	ZDB-GENE-990714-22 (Zebrafish Model Organism Database) 30643 (Entrez Gene) acat2 (Alliance of Genome Resources)	Chr20			NP_571445 (RefSeq) NM_131370 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.