Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LIFR	HGNC:6597 (HGNC) 3977 (Entrez Gene) 151443 (OMIM) LIFR (Alliance of Genome Resources)	Chr5 p13.1	Chr5:38474668-38608403 (-) GRCh38	osteochondrodysplasia	P42702 (UniProt | EBI) NM_001364297 (RefSeq)
mouse	Lifr	MGI:96788 (MGI) 16880 (Entrez Gene) Gene Tree Lifr (Alliance of Genome Resources)	Chr15 3.46 cM	Chr15:7120095-7226970 (+) GRCm39	CAKUT	ENSMUSG00000054263 (Ensembl Gene Model) ENSMUSP00000064551 (Ensembl) ENSMUST00000067190 (Ensembl)
rat	Lifr	RGD:621431 (Rat Genome Database) 81680 (Entrez Gene) Lifr (Alliance of Genome Resources)	Chr2 q16			O70535 (UniProt | EBI) NM_031048 (RefSeq)
zebrafish	lifra	ZDB-GENE-050327-16 (Zebrafish Model Organism Database) 541493 (Entrez Gene) lifra (Alliance of Genome Resources)	Chr5			NP_001014328 (RefSeq) NM_001014306 (RefSeq)
	lifrb	ZDB-GENE-080107-2 (Zebrafish Model Organism Database) 565104 (Entrez Gene) lifrb (Alliance of Genome Resources)	Chr21			NP_001107204 (RefSeq) NM_001113732 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.