Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MITF	HGNC:7105 (HGNC) 4286 (Entrez Gene) 156845 (OMIM) MITF (Alliance of Genome Resources)	Chr3 p13	Chr3:69739456-69968336 (+) GRCh38	familial melanoma Tietze's syndrome Tietz syndrome Waardenburg syndrome Waardenburg syndrome type 2A	O75030 (UniProt | EBI) NM_198158 (RefSeq)
mouse	Mitf	MGI:104554 (MGI) 17342 (Entrez Gene) Gene Tree Mitf (Alliance of Genome Resources)	Chr6 45.05 cM	Chr6:97784013-97998310 (+) GRCm39	Camurati-Engelmann disease ocular albinism with sensorineural deafness osteopetrosis Tietz syndrome Waardenburg syndrome type 1 Waardenburg syndrome type 2A	ENSMUSG00000035158 (Ensembl Gene Model) ENSMUSP00000044938 (Ensembl) ENSMUST00000043637 (Ensembl)
rat	Mitf	RGD:3092 (Rat Genome Database) 25094 (Entrez Gene) Mitf (Alliance of Genome Resources)	Chr4 q34			O88368 (UniProt | EBI) NM_001398550 (RefSeq)
zebrafish	mitfa	ZDB-GENE-990910-11 (Zebrafish Model Organism Database) 30080 (Entrez Gene) mitfa (Alliance of Genome Resources)	Chr6			NP_570998 (RefSeq) NM_130923 (RefSeq)
	mitfb	ZDB-GENE-010919-1 (Zebrafish Model Organism Database) 114833 (Entrez Gene) mitfb (Alliance of Genome Resources)	Chr23			NP_571922 (RefSeq) NM_131847 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.