Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	WLS	HGNC:30238 (HGNC) 79971 (Entrez Gene) 611514 (OMIM) WLS (Alliance of Genome Resources)	Chr1 p31.3	Chr1:68098459-68233120 (-) GRCh38	Zaki syndrome	Q5T9L3 (UniProt | EBI) NM_001002292 (RefSeq)
mouse	Wls	MGI:1915401 (MGI) 68151 (Entrez Gene) Gene Tree Wls (Alliance of Genome Resources)	Chr3 82.65 cM	Chr3:159545309-159644300 (+) GRCm39	Zaki syndrome	ENSMUSG00000028173 (Ensembl Gene Model) ENSMUSP00000143475 (Ensembl) ENSMUST00000198878 (Ensembl)
rat	Wls	RGD:735139 (Rat Genome Database) 362065 (Entrez Gene) Wls (Alliance of Genome Resources)	Chr2 q45			Q6P689 (UniProt | EBI) NM_199408 (RefSeq)
zebrafish	wls	ZDB-GENE-040426-2161 (Zebrafish Model Organism Database) 406420 (Entrez Gene) wls (Alliance of Genome Resources)	Chr2			NP_998311 (RefSeq) NM_213146 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.