Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KCNQ1	HGNC:6294 (HGNC) 3784 (Entrez Gene) 607542 (OMIM) KCNQ1 (Alliance of Genome Resources)	Chr11 p15.5-p15.4	Chr11:2444654-2849105 (+) GRCh38	atrial fibrillation familial atrial fibrillation Jervell-Lange Nielsen syndrome long QT syndrome long QT syndrome 1 short QT syndrome type 2 diabetes mellitus	P51787 (UniProt | EBI) NM_001406837 (RefSeq)
mouse	Kcnq1	MGI:108083 (MGI) 16535 (Entrez Gene) Gene Tree Kcnq1 (Alliance of Genome Resources)	Chr7 88.12 cM	Chr7:142660614-142980787 (+) GRCm39	Jervell-Lange Nielsen syndrome long QT syndrome 1	16535 (NCBI Gene Model) P97414 (UniProt | EBI) NM_008434 (RefSeq)
rat	Kcnq1	RGD:621503 (Rat Genome Database) 84020 (Entrez Gene) Kcnq1 (Alliance of Genome Resources)	Chr1 q42			Q9Z0N7 (UniProt | EBI) NM_032073 (RefSeq)
zebrafish	kcnq1.1	ZDB-GENE-061214-5 (Zebrafish Model Organism Database) 557498 (Entrez Gene) kcnq1.1 (Alliance of Genome Resources)	Chr7			NP_001116714 (RefSeq) NM_001123242 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.