Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TBX1	HGNC:11592 (HGNC) 6899 (Entrez Gene) 602054 (OMIM) TBX1 (Alliance of Genome Resources)	Chr22 q11.21	Chr22:19756703-19783593 (+) GRCh38	congenital heart disease DiGeorge syndrome epilepsy hypoparathyroidism sensorineural hearing loss tetralogy of Fallot velocardiofacial syndrome ventricular septal defect	O43435 (UniProt | EBI) NM_005992 (RefSeq)
mouse	Tbx1	MGI:98493 (MGI) 21380 (Entrez Gene) Gene Tree Tbx1 (Alliance of Genome Resources)	Chr16 Syntenic	Chr16:18399729-18409412 (-) GRCm39	autism spectrum disorder DiGeorge syndrome otitis media velocardiofacial syndrome	21380 (NCBI Gene Model) P70323 (UniProt | EBI) NM_001373938 (RefSeq)
rat	Tbx1	RGD:1307734 (Rat Genome Database) 360737 (Entrez Gene) Tbx1 (Alliance of Genome Resources)	Chr11 q23			NP_001402633 (RefSeq) NM_001108322 (RefSeq)
zebrafish	tbx1	ZDB-GENE-030805-5 (Zebrafish Model Organism Database) 368206 (Entrez Gene) tbx1 (Alliance of Genome Resources)	Chr5			Q8AXX2 (UniProt | EBI) NM_183339 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.