Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LIN28A	HGNC:15986 (HGNC) 79727 (Entrez Gene) 611043 (OMIM) LIN28A (Alliance of Genome Resources)	Chr1 p36.11	Chr1:26410817-26429728 (+) GRCh38		Q9H9Z2 (UniProt | EBI) NM_024674 (RefSeq)
mouse	Lin28a	MGI:1890546 (MGI) 83557 (Entrez Gene) Gene Tree Lin28a (Alliance of Genome Resources)	Chr4 66.5 cM	Chr4:133730641-133746152 (-) GRCm39	nephroblastoma	ENSMUSG00000050966 (Ensembl Gene Model) ENSMUSP00000050488 (Ensembl) ENSMUST00000051674 (Ensembl)
rat	Lin28a	RGD:1566408 (Rat Genome Database) 500562 (Entrez Gene) Lin28a (Alliance of Genome Resources)	Chr5 q36			NP_001102739 (RefSeq) NM_001109269 (RefSeq)
zebrafish	lin28aa	ZDB-GENE-110914-157 (Zebrafish Model Organism Database) 799825 (Entrez Gene) lin28aa (Alliance of Genome Resources)	Chr16			XP_017206943 (RefSeq)
	lin28ab	ZDB-GENE-040426-747 (Zebrafish Model Organism Database) 394066 (Entrez Gene) lin28ab (Alliance of Genome Resources)	Chr19			Q803L0 (UniProt | EBI) NM_201091 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.