Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IQSEC2	HGNC:29059 (HGNC) 23096 (Entrez Gene) 300522 (OMIM) IQSEC2 (Alliance of Genome Resources)	ChrX p11.22	ChrX:53225813-53321350 (-) GRCh38	non-syndromic X-linked intellectual disability 1	Q5JU85 (UniProt | EBI) NM_001410736 (RefSeq)
mouse	Iqsec2	MGI:3528396 (MGI) 245666 (Entrez Gene) Gene Tree Iqsec2 (Alliance of Genome Resources)	ChrX 68.46 cM	ChrX:150927193-151008232 (+) GRCm39	non-syndromic X-linked intellectual disability	ENSMUSG00000041115 (Ensembl Gene Model) ENSMUSP00000159624 (Ensembl) ENSMUST00000249244 (Ensembl)
rat	Iqsec2	RGD:1596452 (Rat Genome Database) 685244 (Entrez Gene) Iqsec2 (Alliance of Genome Resources)	ChrX q13			NP_001264315 (RefSeq) NM_001277386 (RefSeq)
zebrafish	iqsec2b	ZDB-GENE-081105-73 (Zebrafish Model Organism Database) 797187 (Entrez Gene) iqsec2b (Alliance of Genome Resources)	Chr8			XP_068079274 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.