Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AMY1A	HGNC:474 (HGNC) 276 (Entrez Gene) 104700 (OMIM) AMY1A (Alliance of Genome Resources)	Chr1 p21.1	Chr1:103655519-103664554 (+) GRCh38		P0DUB6 (UniProt | EBI) NM_001008221 (RefSeq)
	AMY1B	HGNC:475 (HGNC) 277 (Entrez Gene) 104701 (OMIM) AMY1B (Alliance of Genome Resources)	Chr1 p21.1	Chr1:103687415-103696454 (-) GRCh38		P0DTE7 (UniProt | EBI) NM_001386925 (RefSeq)
	AMY1C	HGNC:476 (HGNC) 278 (Entrez Gene) 104702 (OMIM) AMY1C (Alliance of Genome Resources)	Chr1 p21.1	Chr1:103745323-103758726 (+) GRCh38		P0DTE8 (UniProt | EBI) NM_001008219 (RefSeq)
	AMY2A	HGNC:477 (HGNC) 279 (Entrez Gene) 104650 (OMIM) AMY2A (Alliance of Genome Resources)	Chr1 p21.1	Chr1:103616651-103625780 (+) GRCh38		P04746 (UniProt | EBI) NM_000699 (RefSeq)
	AMY2B	HGNC:478 (HGNC) 280 (Entrez Gene) 104660 (OMIM) AMY2B (Alliance of Genome Resources)	Chr1 p21.1	Chr1:103553815-103579534 (+) GRCh38		P19961 (UniProt | EBI) NM_020978 (RefSeq)
mouse	Amy1	MGI:88019 (MGI) 11722 (Entrez Gene) Gene Tree Amy1 (Alliance of Genome Resources)	Chr3 49.35 cM	Chr3:113349601-113371399 (-) GRCm39		11722 (NCBI Gene Model) P00687 (UniProt | EBI) NM_007446 (RefSeq)
rat	Amy1	RGD:2113 (Rat Genome Database) 24203 (Entrez Gene) Amy1 (Alliance of Genome Resources)	Chr2 q42			NP_001010970 (RefSeq) NM_001010970 (RefSeq)
zebrafish	amy2a	ZDB-GENE-040426-2393 (Zebrafish Model Organism Database) 406539 (Entrez Gene) amy2a (Alliance of Genome Resources)	Chr2			NP_998176 (RefSeq) NM_213011 (RefSeq)
	amy2al1	ZDB-GENE-040426-1606 (Zebrafish Model Organism Database) 393400 (Entrez Gene) amy2al1 (Alliance of Genome Resources)	Chr17			NP_956722 (RefSeq) NM_200428 (RefSeq)
	amy2al2	ZDB-GENE-040801-179 (Zebrafish Model Organism Database) 445049 (Entrez Gene) amy2al2 (Alliance of Genome Resources)	Chr17			NP_001003729 (RefSeq) NM_001003729 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.