Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MARS1	HGNC:6898 (HGNC) 4141 (Entrez Gene) 156560 (OMIM) MARS1 (Alliance of Genome Resources)	Chr12 q13.3	Chr12:57475445-57517569 (+) GRCh38	Charcot-Marie-Tooth disease axonal type 2U hereditary spastic paraplegia 70 trichothiodystrophy	P56192 (UniProt | EBI) NM_004990 (RefSeq)
mouse	Mars1	MGI:1345633 (MGI) 216443 (Entrez Gene) Gene Tree Mars1 (Alliance of Genome Resources)	Chr10 74.5 cM	Chr10:127132090-127147655 (-) GRCm39		216443 (NCBI Gene Model) Q68FL6 (UniProt | EBI) NM_001171582 (RefSeq)
rat	Mars1	RGD:1305321 (Rat Genome Database) 299851 (Entrez Gene) Mars1 (Alliance of Genome Resources)	Chr7 q22			NP_001121131 (RefSeq) NM_001127659 (RefSeq)
zebrafish	mars1	ZDB-GENE-030219-83 (Zebrafish Model Organism Database) 338183 (Entrez Gene) mars1 (Alliance of Genome Resources)	Chr6			NP_956370 (RefSeq) NM_200076 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.