Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GABRB3	HGNC:4083 (HGNC) 2562 (Entrez Gene) 137192 (OMIM) GABRB3 (Alliance of Genome Resources)	Chr15 q12	Chr15:26543552-26939539 (-) GRCh38	alcohol dependence alcohol use disorder childhood absence epilepsy developmental and epileptic encephalopathy 43 heroin dependence	P28472 (UniProt | EBI) NM_001191320 (RefSeq)
mouse	Gabrb3	MGI:95621 (MGI) 14402 (Entrez Gene) Gene Tree Gabrb3 (Alliance of Genome Resources)	Chr7 33.53 cM	Chr7:57240266-57478550 (+) GRCm39	autism spectrum disorder	14402 (NCBI Gene Model) P63080 (UniProt | EBI) NM_008071 (RefSeq)
rat	Gabrb3	RGD:2651 (Rat Genome Database) 24922 (Entrez Gene) Gabrb3 (Alliance of Genome Resources)	Chr1 q22			P63079 (UniProt | EBI) NM_017065 (RefSeq)
zebrafish	gabrb3	ZDB-GENE-101102-2 (Zebrafish Model Organism Database) 566922 (Entrez Gene) gabrb3 (Alliance of Genome Resources)	Chr6			XP_005166138 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.