Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GABRG2	HGNC:4087 (HGNC) 2566 (Entrez Gene) 137164 (OMIM) GABRG2 (Alliance of Genome Resources)	Chr5 q34	Chr5:162000057-162162977 (+) GRCh38	alcohol dependence alcoholic liver cirrhosis amphetamine abuse childhood absence epilepsy developmental and epileptic encephalopathy 74 familial febrile seizures 8 heroin dependence	P18507 (UniProt | EBI) NM_001375345 (RefSeq)
mouse	Gabrg2	MGI:95623 (MGI) 14406 (Entrez Gene) Gene Tree Gabrg2 (Alliance of Genome Resources)	Chr11 24.8 cM	Chr11:41801030-41891684 (-) GRCm39	generalized epilepsy with febrile seizures plus	ENSMUSG00000020436 (Ensembl Gene Model) ENSMUSP00000063812 (Ensembl) ENSMUST00000070735 (Ensembl)
rat	Gabrg2	RGD:61966 (Rat Genome Database) 29709 (Entrez Gene) Gabrg2 (Alliance of Genome Resources)	Chr10 q21			P18508 (UniProt | EBI) NM_001393775 (RefSeq)
zebrafish	gabrg2	ZDB-GENE-091118-65 (Zebrafish Model Organism Database) 553402 (Entrez Gene) gabrg2 (Alliance of Genome Resources)	Chr21			NP_001243179 (RefSeq) NM_001256250 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.