Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ASPM	HGNC:19048 (HGNC) 259266 (Entrez Gene) 605481 (OMIM) ASPM (Alliance of Genome Resources)	Chr1 q31.3	Chr1:197084121-197146694 (-) GRCh38	microcephaly primary autosomal recessive microcephaly primary autosomal recessive microcephaly 5 visual epilepsy	Q8IZT6 (UniProt | EBI) NM_018136 (RefSeq)
mouse	Aspm	MGI:1334448 (MGI) 12316 (Entrez Gene) Gene Tree Aspm (Alliance of Genome Resources)	Chr1 61.45 cM	Chr1:139382510-139421829 (+) GRCm39	microcephaly	ENSMUSG00000033952 (Ensembl Gene Model) ENSMUSP00000059159 (Ensembl) ENSMUST00000053364 (Ensembl)
rat	Aspm	RGD:1307111 (Rat Genome Database) 289054 (Entrez Gene) Aspm (Alliance of Genome Resources)	Chr13 q13			NP_001099425 (RefSeq) NM_001105955 (RefSeq)
zebrafish	aspm	ZDB-GENE-050208-620 (Zebrafish Model Organism Database) 554173 (Entrez Gene) aspm (Alliance of Genome Resources)	Chr22			NP_001116845 (RefSeq) NM_001123373 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.