Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	FAM53C	HGNC:1336 (HGNC) 51307 (Entrez Gene) 609372 (OMIM) FAM53C (Alliance of Genome Resources)	Chr5 q31.2	Chr5:138331935-138349729 (+) GRCh38		Q9NYF3 (UniProt | EBI) NM_001135647 (RefSeq)
mouse	Fam53c	MGI:1913556 (MGI) 66306 (Entrez Gene) Gene Tree Fam53c (Alliance of Genome Resources)	Chr18 18.72 cM	Chr18:34891959-34906813 (+) GRCm39		ENSMUSG00000034300 (Ensembl Gene Model) ENSMUSP00000037034 (Ensembl) ENSMUST00000049281 (Ensembl)
rat	Fam53c	RGD:1593851 (Rat Genome Database) 685405 (Entrez Gene) Fam53c (Alliance of Genome Resources)	Chr18 p12			NP_001414345 (RefSeq) NM_001427416 (RefSeq)
zebrafish	fam53c	ZDB-GENE-091027-2 (Zebrafish Model Organism Database) 100002393 (Entrez Gene) fam53c (Alliance of Genome Resources)	Chr21			NP_001104709 (RefSeq) NM_001111239 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.