Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CYP8B1	HGNC:2653 (HGNC) 1582 (Entrez Gene) 602172 (OMIM) CYP8B1 (Alliance of Genome Resources)	Chr3 p22.1	Chr3:42856005-42875898 (-) GRCh38		Q9UNU6 (UniProt | EBI) NM_004391 (RefSeq)
mouse	Cyp8b1	MGI:1338044 (MGI) 13124 (Entrez Gene) Gene Tree Cyp8b1 (Alliance of Genome Resources)	Chr9 72.73 cM	Chr9:121743422-121745371 (-) GRCm39		13124 (NCBI Gene Model) O88962 (UniProt | EBI) NM_010012 (RefSeq)
rat	Cyp8b1	RGD:71016 (Rat Genome Database) 81924 (Entrez Gene) Cyp8b1 (Alliance of Genome Resources)	Chr8 q32			NP_112520 (RefSeq) NM_031241 (RefSeq)
zebrafish	cyp8b1.1	ZDB-GENE-040808-53 (Zebrafish Model Organism Database) 445281 (Entrez Gene) cyp8b1.1 (Alliance of Genome Resources)	Chr2			NP_001003736 (RefSeq) NM_001003736 (RefSeq)
	cyp8b1.2	ZDB-GENE-080212-9 (Zebrafish Model Organism Database) 100004274 (Entrez Gene) cyp8b1.2 (Alliance of Genome Resources)	Chr2			NP_001103758 (RefSeq) NM_001110288 (RefSeq)
	cyp8b1.3	ZDB-GENE-040912-153 (Zebrafish Model Organism Database) 447848 (Entrez Gene) cyp8b1.3 (Alliance of Genome Resources)	Chr2			NP_001004587 (RefSeq) NM_001004587 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.